Hair growth potential of Helianthus annuus seed oil extract and Martynia annua seed oil extract on albino mice

Authors

  • Abhishek Kumar Department of Pharmacology, Vedica College of B. Pharmacy, RKDF University, Bhopal, Madhya Pradesh, India
  • Mohan Lal Kori Department of Pharmacology, Vedica College of B. Pharmacy, RKDF University, Bhopal, Madhya Pradesh, India

DOI:

https://doi.org/10.25004/IJPSDR.2024.160201

Keywords:

Helianthus annuus, Martynia annua, Growth, Minoxidil, Phytochemical, Hair growth

Abstract

The surface scalp of hair matrix cells differentiation during migration induces by vigorous proliferation result hair growth. The objective of current investigation was to explore the needs to know of Helianthus annuus seed oil extract and Martynia annua seed oil extract as a potential of hair growth. In albino mice on to the back skin surface spread prepared oil extract to assess telogen to anagen phase transition. The quantitative and qualitative analysis was performed and observed. The outcomes of their research revealed that Helianthus annuus seed oil extract of petroleum ether and Martynia annua oil extract of petroleum ether in combination shows exhibited prominent activity. In different dosage of petroleum ether oil extract of both plant combinations of dosage applied topically 10 mg/ml, 20 mg/ml and 30 mg/ml, in to the shaved skin of albino mice treated groups observed for 21 days. Result shown that petroleum ether oil extract of both plant in combination shown significantly hair growth potential in a different dosage dependent manner observed, particularly on albino mice. Albino mice groups treated with petroleum ether 30 mg/ml of both plants required shorter time to the control (positive) group and 2% minoxidil (standard) group at different growth stages. The hair length of albino mice treated with petroleum ether 30 mg/ml oil extract of both plants showed remarkable increase 21.35±0.25 mm. and the thickness of hair of albino mice group treated with combination of both plant oil extract is 0.020±0.0010 mm with respect to 2% minoxidil (0.021±0.008). These finding suggested that Helianthus annus seed oil extract and Martynia annua oil extract have the potential of show hair growth.

Downloads

Download data is not yet available.

References

Abreu CM, Marques AP. Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls. Bioengineering & Translational Medicine.2022;7:1-18. Available from: DOI: 10.1002/btm2.10235

Stough D, Stenn K, Haber R, Parsley WM, Vogel JE, Whiting DA, Washenik K. Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men. Mayo Clinical Process. 2005;80(10):1316-1322. Available from: doi: https://doi.org/10.4065/80.10.1316

Cash FT. The psychology of hair loss and its implications for patient care. Clinics in Dermatology. 2001; 19:161-166. Available from: DOI: 10.1016/s0738-081x(00)00127-9

Hibino T, Nishiyama T. Role of TGF-beta2 in the human hair cycle. Journal Dermatol Sci. 2004;35(1):9-18. Available from: DOI: 10.1016/j.jdermsci.2003.12.003

Venning VA, Dawber RP. Patterned androgenic alopecia in women. J. Am. Acad. Dermatol. 1988; 18:1073-1077. Available from: DOI: 10.1016/s0190-9622(88)70108-5

Datta K, Singh AT, Mukherjee A, Bhat B, Ramesh B, Burman AC. Eclipta alba extract with potential for hair growth promoting activity. J. Ethno pharmacol. 2009; 124: 450-456. Available from: DOI: 10.1016/j.jep.2009.05.023

Vaidya ADB, Devasagayam TPA. Current Status of Herbal Drugs in India: An Overview. Journal of Clinical Biochemistry and Nutrition. 2007; 41(1):1-11. Available from: DOI: https://doi.org/10.3164/jcbn.2007001

Hwang D, Lee H, Lee J, Lee M, Cho S, Kim T and Kim H. Micro-Current Stimulation Has Potential Effects of Hair Growth-Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model. International Journal Molecular Science. 2021; 22, 4361:1-16. Available from: DOI:10.3390/ijms22094361

Abubakar AR, Haque M. Preparation of medicinal plants: Basic extraction and fractionation procedures for experimental purposes. Journal of Pharmacy and BioAllied Science. 2020; 12:1-10. Available from: doi: 10.4103/jpbs.JPBS_175_19

Kenwat R, Prasad P, Satapathy T, Roy A. Martynia annua: An Overview. UK Journal of Pharmaceutical and Biosciences. 2013; 1,1: 7-10. Available from: DOI:10.20510/ukjpb/1/i1/91102

Lodhi S, Jain A, Jain AP, Pawar RS, Singhai AK. Effects of flavonoids from Martynia annua and Tephrosia purpurea on cutaneous wound healing. Avicenna J Phytomed, 2016; 6 (5): 578-591. Available from: doi: 10.22038/AJP.2016.6760

Dhingra AK, Chopra B, Mittal SK. Martynia annua L.: A Review on Its Ethnobotany, Phytochemical and Pharmacological Profile. Journal of Pharmacognosy and Phytochemistry. 2013;1(6):135-140.Online Available at : www.phytojournal.com

Kirtikar KR, Basu BD. Indian medicinal Plants. Edn 2, Vol. I, International Book Distributors, Deharadun, 1987, pp.1854-1855. Available from:

Nestor MS, Ablon G, Gade A, Han H and Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. Journal Cosmet Dermatol. 2021; 20(12): 3759–3781. Available from: DOI: 10.1111/jocd.14537

Venkataram Mysore. Finasteride and sexual side effects. Indian Dermatol Online Journal. 2012; 3(1): 62–65. Available from: doi: 10.4103/2229-5178.93496

Nadeem R, Iqbal A, Zia MA, Anwar F, Shahid SA, Mahmood Z, Shafeeq A, Akhtar N. Effect of Cold-Pressing and Soxhlet Extraction on the Physico-Chemical Attributes of Sunflower (Helianthus annuus L.) Seed Oil. International Journal of Chemical and Biochemical Sciences. 2015; 7; 41-46. Available from:

Akter A, Neela FA, Khan MSI, Islam MS and Alam MF. Screening of Ethanol, Petroleum Ether and Chloroform Extracts of Medicinal Plants, Lawsonia inermis L. and Mimosa pudica L. for Antibacterial Activity. Indian Journal of Pharm Science. 2010; 72(3): 388-392. Available from: doi: 10.4103/0250-474X.70492

Kaushik S, Jain P, Satapathy T, Purabiya P, Roy A. Evaluation of anti-arthritic and anti inflammatory activities of Martynia annua L. Ethanolic extract. Clinical Phytoscience. 2021;7(7):1-11 Available from: Doi:https://doi.org/10.1186/s40816-021-00250-y

Lulekala E, Tesfayeb S, Gebrechristosc S, Diresc K, Zenebec T, Zegeyec N, Feleked G, Kassahund A, Shiferawd Y, Mekonnen A. Phytochemical analysis and evaluation of skin irritation, acute and subacute toxicity of Cymbopogon citratus essential oil in mice and rabbits. Toxicology Reports.2019;6:1289-1294. Available from: DOI: 10.1016/j.toxrep.2019.11.002

Truong VL, Keum YS, Jeong WS. Red ginseng oil promotes hair growth and protects skin against UVC radiation. Journal of Ginseng Research.2021; 45: 498 -509. Available from: DOI: https://doi.org/10.1016/j.jgr.2020.12.008

Park JH, Ho YH, Manonuku K. Hair diameter measurement methods: micrometer caliper versus phototrichogram. Archives of Aesthetic Plastic Surgery. 2023; 29:97-101. Available from: DOI:10.14730/aaps.2022.00423

Seo SR, Kang G, Ha JW, Kim JC. In vivo hair growth-promoting efficacies of herbal extracts and their cubosomal suspensions, Journal of Industrial and Engineering Chemistry.2013;19:1331-1339. Available from: DOI: 10.1016/j.jiec.2012.12.037

Singh A, Pandey S, Srivastava RP, Devkota HP, Singh L, Saxena G. Helianthus annuus L.: Traditional uses, phytochemistry and pharmacological activities. Springer book 2022; 12: 2-26. Available from: DOI:10.1007/978-981-19-6080-2_12

Roy RK, Thakur M, Dixit VK. Development and evaluation of polyherbal formulation for hair growth–promoting activity. Journal of Cosmetic Dermatology.2007;6:108-112. Available from: DOI: 10.1111/j.1473-2165.2007.00305.x

Roy RK, Thakur M, Dixit VK. Hair growth promoting activity of Eclipta alba in male albino rats. Archives of Dermatological Research. 2008; 300:357-364. Available from: DOI 10.1007/s00403-008-0860-3

Madaan A, Verma R, Singh AT, Jaggi M. Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth. International Journal of Cosmetic Science 2018: 1-22. Available from: DOI: 10.1111/ics.12489

Downloads

Published

30-03-2024

Issue

Section

Research Article

How to Cite

“Hair Growth Potential of Helianthus Annuus Seed Oil Extract and Martynia Annua Seed Oil Extract on Albino Mice”. International Journal of Pharmaceutical Sciences and Drug Research, vol. 16, no. 2, Mar. 2024, pp. 135-41, https://doi.org/10.25004/IJPSDR.2024.160201.